Research
Our research labs are well equipped and have most of modern equipments necessary for research in molecular biology, microbiology, diagnostics and biomarkers. GMERF has internal long-term research projects for PhD and also designs short-term research projects to help undergraduate and postgraduate students of life sciences from our associate universities and colleges with whom we have signed Memorandum of Understanding. GMERF has successfully offered research projects to more than 35 students so far. Our research projects offer comprehensive training to students in research literature search, scientific presentations, communication/presentation skills, designing experiments, interpreting results and writing manuscripts for publications. Many students have published their first ever research papers from GMERF and got admission to MS degree in US universities. Our own staff members are pursuing their PhD programs in Biotechnology.
The laboratory and Dr. Ch. Lakshmi Kiran are recognized for PhD program for Biotechnology under Department of Genetics & Biotechnology, Osmania University.
The laboratory is recognised by Biotechnology Consortium of India to offer Industrial training in Transplant Biology, Immunology, Genomics, Molecular Diagnostics and Biomarkers.
The laboratory is engaged in research in the following two frontier areas:
- Sepsis-Proteomics
- Acute Kidney Injury-Biomarkers
- Molecular mechanisms of drug resistance in microbial pathogens.
- Quorum sensing and Bio film formation in S.auveus and A.baunanii.
- Tissue typing for all organ transplants and related biology
- HLA typing
- Lymphocyte Cross match
- Donor Specific Antibodies
- Panal Reactive Antibodies
- Molecular Diagnostics – RT- PCR
- HBV
- HCV
- CMV
- HIV
| No. | Title of Project | Funding Agency | Amount | Date of sanction and Duration | investigator/co-investigator |
|---|---|---|---|---|---|
| 1 | Functional restoration of infarcted/scarred myocardium through transplantation of bone marrow stem cells [PI] | GMERF Intramural | INR 500,000 | November 2005/ 4 years | Lakshmi Kiran Chelluri |
| 2 | Intra-coronary autologous stem cell transplantation in acute myocardial infarction(AMI) [PI] | GMERF Intramural | INR 500,000 | November 2005/ 4years | Lakshmi Kiran Chelluri |
| 3 | Autologous stem cell transplantation in Ischemic cardiomyopathy with diffuse coronary artery disease (CAD) [PI] | GMERF Intramural | INR 500,000 | Completed | Lakshmi Kiran Chelluri |
| 4 | Regeneration of chronic injured spinal cord by stem cell transplantation: A clinical trial [PI] | GMERF Intramural | INR 500,000 | Completed | Lakshmi Kiran Chelluri |
| 5 | The immunological and molecular studies in tuberculosis patients to understand the high prevalence of the disease in younger age groups- scheme for young scientists- Co-Investigator | DBT 102/IFD/PR 2029/2007- 2008 Extramural | INR 6,25,000 | Completed | Lakshmi Kiran Chelluri |
| 6 | In vitro transdifferentiation of bone marrow mesenchymal stem cells into insulin secreting [Phase I trial] [Key Investigator] | DST SR/NM/NAT- 03/2006 Extramural | INR 29,50,00 | 2007-2009 Completed | Lakshmi Kiran Chelluri |
| 7 | Bovine Serum Albumin (BSA) in PCR amplification – potential application in clinical diagnostics [PI] | GMERF Intramural | INR 200,000 | Completed | Lakshmi Kiran Chelluri |
| 8 | Detection of SNP in IL-10 promoter gene as a diagnostic parameter in SLE patients [PI] | GMERF Intramural | INR 100,000 | Completed | Lakshmi Kiran Chelluri |
| 9 | Functional evaluation of autologous cell based therapy in cardiovascular diseases – Molecular Imaging[An innovative non-invasive technology]-Key Investigator | BT/BIPP0296/ 07/10-DBT Extramural | 737 Lakhs | 2012-2013 | Lakshmi Kiran Chelluri |
| 10 | Microenvironment profiling of the stromal cell interaction with bioengineered extra cellular matrix (ECM) in tissue injury | GMERF Intramural | INR 5 Lakhs | 2012-2015 | Lakshmi Kiran Chelluri |
| 11 | A study on the immunotherapeutic strategies in autoimmune diseases | GMERF | INR 5 Lakhs | 2012-2015 | Lakshmi Kiran Chelluri |
| 12 | Design and Development of a Rapid Point-of-Care Device for Endotoxin Detection in Critically Ill/Septicemia Patients. | DBT Extramural | INR 28 Lakhs | 2013-15 | Dr.V.Sritharan |
| 13 | Development of multiplex PCR and Real Time PCR assay systems for the identification of Methicillin Resistant Staphylococcus aureus (MRSA) (PI) | SBIRI Project under DBT | 14.5 Lakhs | 2014-2016 | Dr.V.Sritharan |
| 14 | De-Cellularization and re-cellularization of rat liver matrix scaffold – Mentor to National PDF SERB fellow | DST-SERB Extramural | INR 19.5 L | 2017-2019 | Lakshmi Kiran Chelluri |
| 15 | Cell death mechanisms in Infection and Inflammation | Indo-US Collaboration | - | 2017-2020 | Lakshmi Kiran Chelluri |
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Last updated on October 18th 2021